Dog Health Alert About Evamist

By Cheryl Campbell | Canine Health

Dog Health Alert About Evamist

Dog Health Alert About Evamist

This article appears on FDA’s Consumer Updates page, which features the latest information on all FDA-regulated products. A Dog Health Alert About Evamist is listed so I felt it was important to share.

The Food and Drug Administration (FDA) Recommends Keeping Children and Pets Away from Evamist

Evamist contains the estrogen hormone estradiol. Sprayed inside the forearm between the elbow and wrist, the FDA reports adverse events in children and pets inadvertently exposed to the drug.

Adverse events reported in unintentionally exposed children include

  • premature puberty, nipple swelling, and breast development in girls
  • breast enlargement in boys

FDA has also received reports of inadvertent exposure in pets. Pets exposed to Evamist may exhibit signs such as mammary/nipple enlargement and vulvar swelling.

“Women using Evamist need to be aware of the potential risks to children who come in contact with the area of skin where this drug is applied,” says Julie Beitz, M.D., a director of drug evaluation with FDA. “It is important that people know to keep both children and pets away from the product to minimize exposure.”

Advice for Consumers

FDA recommends that women using Evamist not allow children or pets to contact the area of the arm where Evamist was sprayed.

  1. Small pets are especially sensitive to the estrogen in Evamist. Contact a veterinarian if your pet shows signs of nipple and/or vulvar enlargement, or any other sign of illness
  2. Women should cover the arm where Evamist was sprayed if they know they cannot keep a child or pet from making contact with their arm.
  3. You should talk with your healthcare professional if you have questions about the possibility of exposing a child to Evamist.
  4. Read the patient package insert when picking up a prescription for Evamist

If Contact Occurs

When a child comes in contact with Evamist the FDA recommends the following:

  • wash the child’s skin with soap and water as soon as possible
  • contact the child’s health care professional if the child begins to have any of the following signs or symptoms:
    1. nipple or breast swelling
    2. breast tenderness in girls
    3. breast enlargement in boys.

You can report any side effects from the use of Evamist to FDA’s MedWatch Adverse Event Reporting Program online or by mail, fax, or phone.

  • Regular Mail: Use postage-paid, pre-addressed FDA form 3500
  • Fax: 1-800-FDA-0178
  • Phone: 1-800-332-1088

At this time, it is unknown whether unintended exposure can occur with other topical (applied to the skin) estrogen products.

FDA continues to review adverse event reports and evaluate ways to reduce unintended exposures.

Legal Disclaimer

If your pet is showing any signs of distress or you suspect your pet is seriously ill, CONTACT YOUR VETERINARIAN immediately.